Absolute contraindications
✅ blood diseases, disorders of hematopoietic function: lymphogranulomatosis, leukemia, hemolytic anemia, thalassemia;;
✅ chronic somatic diseases of the body: diabetes mellitus, diseases of the oral mucosa, diabetes with insulin dependence, rheumatic disease, tuberculosis;
✅ pathologies in the endocrine system: severe forms of hyper- and hypothyroidism, hyper- and hypoparathyroidism, pathology of the adrenal glands, pituitary gland;
✅ serious disorders in the immune system: severe infections, lupus erythematosus, hypoplasia of the thymus and parathyroid glands, polymyositis;
✅ pathologies of the skeletal system, creating insurmountable obstacles to the normal regeneration of bone tissue: congenital osteopathy, osteoporosis, dysplasia, osteonecrosis;
✅ diseases of the oral mucosa: Sjogren’s syndrome, lupus erythematosus, pemphigus, chronic recurrent aphthous stomatitis;
✅ severe forms of diseases of the cardiovascular system;
✅ immunodeficiency states and diseases of the thyroid gland;
✅ pathologies of the central and peripheral nervous system: psychoses, neuroses, drug addiction, alcoholism, schizophrenia, dementia, paranoia;
✅ systemic connective tissue diseases with manifestation in the maxillofacial region;
✅ AIDS and sexually transmitted diseases;
✅ malignant tumors;
✅ osteoradionecrosis;
✅ clinical intolerance to metals;
✅ systemic connective tissue diseases with their manifestation in the maxillofacial region;